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The
Molecular Medicine department was established in 2008
after its separation from Biotechnology department to have independent
activities in different fields. This center has three subdivisions including
Genome & human genetic disorders lab, Cellular-Molecular Therapy lab and
PND (pre-natal diagnosis).
The
PND lab as a National Reference lab is mainly focused on PND of
Thalassemia, Hemoglobinopathies and DMD. The Cellular-Molecular Therapy lab do
some research on cell therapies and molecular therapies for various kinds of
genetic disorders such as immunodeficiency diseases, hemophilia and PKU, and
cancer biomarkers especially, breast, lung, prostate, colon and leukemia. The
Genome & human genetic disorders lab perform NGS studies such as exom
sequencing analysis on different genetic disorders.
The
PND lab activities:
1- The PND section of Genetic lab was active since 1994
in Biotechnology department. From the time of establishment of Molecular
Medicine Center as an independent department the PND section initiate its role
in acceptance of Thalassemia carriers families and perform the essential
diagnostic test on them. Furthermore, This section has a main key role in training
of laboratory experts from other genetic laboratories and transferring the
technology of PND. Moreover, the members of this section have some activities
in periodic visit of other laboratories undrer supervision of Disease Management Center.
2- Developing Standards and Extend Quality Assesment
Programms (EQA). This center had some projects on preparation of immortal cells
in different dieases including Thalassemia and PKU. Also, it acts out to
perform EQA progframms with coordination of Ministery of Health in order to
examine the function of leboratoris member of PND. The faculty members of this
department with cooperation of the Center of Disease Management proceed to
prepare National Guidelines for PND, Hemophilia, DMD, PKU and other dieases.
The
List of the Faculty Members of Molecular Medicine Center & their Fields of
Interest:
Prof. Reza
Mahdian ( The
Head of the department): Cancer genetics, Biomarkers for Diagnosis and
Prognosis, Prostate cancer, Breast cancer, Immunodeficiency disoreders
Prof. Siros
Zeinali: Medical
Genetics, Population Genetics, Forensic Genetics, Prenatal Diagnosis
Dr. Morteza
karimipoor: Gene
therapy of Thalassemia and Hemophilia, Genome Editing, Cancer biomarkers
investigation
Dr. Ladan
Teimori:
Designing peptides, Targeted Therapy, Colon Cancer, Resistance mechanism, Gene
Therapy
Dr. Mohammad
Hamid: Chronic
Myloid leukemia, NGS and minisequencing of multifactorial and polygenic
diseases.
Dr.
Esmat Mirabzadeh Ardakani:
Laboratory Animals, Animal Models, Ethics in Medical Science
Dr. Hamzeh
Rahimi: Protein
Engineering, NGS Analysis, Exom Sequencing, RNA sequencing
Dr. Elham
Davoodi:
Thalassemia, Genetic Consulting, PND
Dr. Masoomeh
Azizi: Breast
Cancer, microRNA, Epigenetics, Biomarkers for early Diagnosis
Contact
Phone:
+982164112400
Fax:
+982166480780
Email: dr.reza.mahdian@gmail.com
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