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Bone mass and microarchitecture in T2DM patients and corticosteroids therapy: the Bushehr Elderly Health program

Purification of alkaline phosphatase from bovine milk through metal ion affinity by a novel magnetic nanocomposite based on functionalized chitosan with dopamine and nickel

Novel magnetic organic-inorganic hybrids based on aromatic polyamides and ZnFe2O4 nanoparticles with biological activity

Design and synthesis of a novel nanocomposite based on magnetic dopamine nanoparticles for purification of alpha-amylase from the bovine milk

Novel G-CSF conjugated anionic globular dendrimer: Preparation and biological activity assessment

Trastuzumab Charge Variants: a Study on Physicochemical and Pharmacokinetic Properties

A novel nanocomposite containing zinc ferrite nanoparticles embedded in carboxymethylcellulose hydrogel plus carbon nitride nanosheets with multifunctional bioactivity

Magnetic carboxymethyl cellulose-silk fibroin hydrogel: A ternary nanobiocomposite exhibiting excellent biological activity and in vitro hyperthermia of cancer therapy

Fabrication and investigation of a pentamerous composite based on calix[4]arene functionalized graphene oxide grafted with silk fibroin, cobalt ferrite, and alginate

Investigation of the biological activity, mechanical properties and wound healing application of a novel scaffold based on lignin–agarose hydrogel and silk fibroin embedded zinc chromite nanoparticles

Identification of immunodominant proteins of Leishmania infantum by immunoproteomics to evaluate a recombinant multi-epitope designed antigen for serodiagnosis of human visceral leishmaniasis

A Novel Fc-Engineered Anti-HER2 Bispecific Antibody with Enhanced Antitumor Activity

A validated polyclonal antiserum-based immunoassay for assessment of HPV 16 L1 relative potency

Recent advances on biomedical applications of gellan gum: A review

Agar-tragacanth/silk fibroin hydrogel containing Zn-based MOF as a novel nanobiocomposite with biological activity

Chemical and physical modification of graphene oxide nano-sheets using casein, Zn-Al layered double hydroxide, alginate hydrogel, and magnetic nanoparticles for biomedical applications

Induction of heat shock protein expression in SP2/0 transgenic cells and its effect on the production of monoclonal antibodies

Unveiling the synergy: Biocompatible alginate-cellulose hydrogel loaded with silk fibroin and zinc ferrite nanoparticles for enhanced cell adhesion, and anti-biofilm activity

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The Medical Biotechnology Group > Protein Chemistry Research Unit (Dr. Behroz Vaziri)

The main research activities of this unit are to achieve new vaccines, biomarkers or target drug molecules, for which two-dimensional electrophoresis technique is used to prepare the protein map. Some of the research projects that have been done or are being implemented include:

Proteomics of BHK cells, neuroblastoma, mouse brain and human brain infected with rabies virus using two-dimensional electrophoresis technique and mass spectrometry, study of the splenic lymphocyte proteome of mice infected with two different strains of rabies virus, searching for diagnostic biomarker in the serum of people with gastric cancer, examination of RP-HPLC and differences between Aspergillus fumigatus wild-type proteome and mutant axc4 strain, Launching the Cappillary Electrophoresis system as a new and fast technique for the study of proteomics and analysis of peptides and pharmaceutical proteins.

Moreover, provision of analytical services for amino acids, peptides and proteins in order to qualitatively control recombinant or synthetic protein drugs to research centers and pharmaceutical factories is another activity of this group.

 

 
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