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Molecular and in Silico Analysis of MEFV Variants in Familial Mediterranean Fever Patients in Southwest Iran

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Malaria and Vector Research Group > National Insectarium (Center for Research, Development and Training of Vector-borne Diseases)

Following the WHO/EMRO request from MVRG in 2004, National Insectarium was established with 450 square meters of infrastructure. Then, it started working with full capacity at the Pasteur Institute of Iran in 2010 and its goal is to provide advanced study conditions for specialists and researchers at national and international centers in the field of knowledge frontiers for research on arthropods and vector insects and pathogens causing vector-borne diseases (VBD) in order to:

1. To provide the same opportunity for all Iranian researchers, WHO/EMRO and the International Network of the Institute Pasteur (RIIP).

2. To create opportunities for collaboration on applied studies and genomics to control vector-borne diseases.

Different laboratories and departments in the National Insectarium are as follows:

- Insect breeding laboratories: Routine breeding of Culicidae mosquitoes (species of Anopheles, Culex and Aedes) as well as breeding of phlebotomus, fleas, ticks, myiasis flies and scorpion if necessary and in accordance with the executive period of related projects.

- Laboratory of Morphological Studies: Identification, dissection, and provision of morphological keys and systematic comparisons.

- Laboratory of Study on Insecticides: Conducting routine WHO sensitivity tests for various arthropods that are considered to be important in medical science.

- Laboratory of Molecular Studies: Implementation of various activities including DNA extraction, RNA, PCR, RT-PCR, RFLP, Real-time PCR, cloning, protein expression, protein purification, bioinformatics analysis.

- Cell Culture Laboratory: in vitro permanent culture of plasmodium falciparum parasite, cell culture of insects.

- Laboratory of Microbiology and Paratransgenics: Identification of important microbial flora of medical arthropods for the development and application of paratransgenic technique.

- Laboratory of Molecular Candidates in Anophele vector (An. stephensi): that are involved in the evolution of the parasitic sex life.

- Laboratory for the Study of Natural Products of Vectors and Arthropods: Molecular examination and detection of insect proteins with medical application.

- Challenge Laboratory for the Development of Malaria Vaccine and Appropriate Candidates: For use in paratransgenic technique.

- Laboratory for the design, development and synthesis of insecticides

- Biological Bank: For important medical arthropods and pathogens that are transmitted through them.


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