beta-chitin/silk fibroin/nanohydroxyapatite (CT/SF/nHAp) composite scaffolds were synthesized using freeze-drying

method by blending -chitin hydrogel, silk fibroin and nHAp in the inorganic/organic different weight ratio. The

prepared nHAp and composite scaffolds were characterized using BET, SEM, EDS, FT-IR, XRD and TGA studies.

The composite scaffolds were found to have 80 87% porosity with well-defined interconnected porous construction.

Moreover, the cell viability, attachment and proliferation using MTT, DMEM solution, and mouse preosteoblast cell

proved the cytocompatibility nature of the composite scaffolds with well improved proliferation and cell attachment.

These results imply that these materials can be an ability to be a candidate for bone tissue engineering applications.